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Question 1 Answer 1

The tests we would recommend would include

1. 50:50 mixing studies - if corrects then...
2. Factor XI levels (most likely)
3. Factor VIII and IX (less likely to be a carrier given the absence of family history)
4. Factor XII (but unlikely given the bleeding history)

Her results

APTT             31.2 (50:50 mix)
Factor XI        21%
Factor VIII / IX / XII normal

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