Practice Questions‎ > ‎Clotting‎ > ‎Question 4‎ > ‎

Question 4 Answer 1

The possible causes include:
  1. von Willebrands disease (type II N) - misdiagnosed as haemophilia carrier
  2. Surgical bleeding with associated coagulopathy
Further investigations would include:
  1. Repeat FVIII level
  2. vWF factor VIII binding studies
These confirm a rapid fall in the factor VIII level and reduced binding of vWF to FVIII

  1. Concentrate containing vWF and FVIII - e.g. Haemate P
  2. Repeat FVIII levels (aiming for 100 intraop and >50 until wound healinG
  3. TED stockings only as thromboprophlyaxis